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Structure of 65873-73-6
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5-Bromo-6-methoxynicotinaldehyde delivers a reactive aldehyde handle flanked by electron-withdrawing bromo and methoxy substituents, enabling efficient coupling in cross-coupling and condensation reactions. This bench-stable, moisture-tolerant building block integrates seamlessly into complex heterocyclic architectures.
5-Bromo-6-methoxynicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling direct incorporation of bromo and methoxy functionalities into heterocyclic scaffolds. Its aldehyde group facilitates nucleophilic addition, reductive amination, and coupling reactions with amines or hydrazines, while the bromine atom supports palladium-catalyzed cross-coupling transformations. The methoxy substituent enhances solubility and modulates electronic properties, contributing to improved stability and handling during synthesis. This compound functions effectively in the construction of advanced intermediates for pharmaceutical development and functional materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: