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CS-W001157 4
Total: USD 88.00

Biphenyl-3-sulfonyl chloride

  • CAS No. 65685-01-0

  • Cat. No. CS-0071457
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Biphenyl-3-sulfonyl chloride|CS-0071457

Structure of 65685-01-0

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General Information

  • CAS No. 65685-01-0
  • Cat. No. CS-0071457
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉ClO₂S
  • Molecular Weight 252.72
  • Synonym(s) 3-Phenylbenzenesulfonyl chloride
  • SMILES O=S(C1=CC(C2=CC=CC=C2)=CC=C1)(Cl)=O

Description

Biphenyl-3-sulfonyl chloride features a sulfonyl chloride group attached to a biphenyl scaffold, enabling direct incorporation into sulfonamide derivatives. This electron-deficient moiety facilitates nucleophilic substitution under mild conditions and offers enhanced stability in handling compared to more reactive acyl chlorides.

Application

Biphenyl-3-sulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of a biphenylsulfonyl group into target molecules. It enables selective sulfonation of amines, alcohols, and thiols under mild conditions, offering high functional group tolerance and ease of purification. The robust biphenyl scaffold enhances stability and provides a rigid platform for downstream derivatization in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   3.2811
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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