5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride

Name: 5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 342405-38-3
Cat. No. CS-0089460
Purity≥95%
MDL No.MFCD02681919

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride|CS-0089460

Structure of 342405-38-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 342405-38-3
Cat. No. CS-0089460
Purity ≥95%
MDL No. MFCD02681919
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₉ClN₂O₂S
Molecular Weight 256.71
Synonym(s) 5-methyl-1-phenyl-pyrazole-4-sulfonyl chloride
SMILES O=S(C1=C(C)N(C2=CC=CC=C2)N=C1)(Cl)=O

Description

5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride features a reactive sulfonyl chloride group flanked by an electron-rich pyrazole core and a phenyl substituent. This combination enables efficient coupling in synthetic transformations, particularly in the construction of sulfonamide derivatives for medicinal chemistry applications. The methyl group enhances steric and electronic tuning, while the bench-stable nature facilitates handling under standard conditions.

Application

5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride serves as a versatile sulfonyl chloride building block for the synthesis of pyrazole-based sulfonamides and sulfonate esters. Its reactivity enables efficient coupling with amines and alcohols under mild conditions, facilitating rapid access to functionalized heterocycles. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry campaigns and process-scale synthesis.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 51.96
LogP 2.10822
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

342405-38-3 sigma342405-38-3 manufacturer342405-38-3 price342405-38-3 structure342405-38-3 SDSbuy 342405-38-3342405-38-3 supplier342405-38-3 uses342405-38-3 molecular weightprice of 342405-38-3342405-38-3 chemical name formula of 342405-38-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Methyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride

CAS No. 342405-38-3

Recommended Products