Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid

  • CAS No. 65632-62-4

  • Cat. No. CS-W009071
  • Purity≥97%
  • MDL No.MFCD09751404

*For research and further manufacturing use only, not for direct human use.

(S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid|CS-W009071

Structure of 65632-62-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 65632-62-4
  • Cat. No. CS-W009071
  • Purity ≥97%
  • MDL No. MFCD09751404
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆N₂O₄
  • Molecular Weight 264.28
  • Synonym(s) (S)-1-(Benzyloxycarbonyl)hexahydropyridazine-3-carboxylic acid
  • SMILES O=C(N1CCC[C@@H](C(O)=O)N1)OCC2=CC=CC=C2

Description

This chiral building block features a protected hexahydropyridazine core with a benzyloxycarbonyl group and carboxylic acid functionality. It integrates readily into peptide-like architectures, offering a rigid, electron-deficient scaffold for medicinal chemistry applications. The benzyl protecting group enables orthogonal deprotection under standard hydrogenolysis conditions.

Application

(S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid serves as a stereochemically defined building block for the synthesis of pyridazinone-based scaffolds. Its benzyloxycarbonyl (Cbz) group provides robust protection of the amine, enabling selective deprotection and orthogonal functionalization. The carboxylic acid functionality facilitates coupling reactions with amines or alcohols under standard conditions. This compound exhibits good bench stability and simplifies purification in multi-step syntheses, making it valuable for medicinal chemistry campaigns targeting heterocyclic compounds.

Synthesis

  • Route1
    • null|null
      672307-41-4
    • ~68%
    • In-stock
      (S)-1-((Benzyloxy)carbonyl)hexahydropyridazine-3-carboxylic acid|CS-W009071
      65632-62-4

    References

    • Coats, Reed A.; Lee, Sheng-Lian; Davis, Kari A.; Patel, Kanu M.; Rhoads, Elaine K.; Howard, Michael H. Journal of Organic Chemistry, 2004 , vol. 69, # 5 p. 1734 - 1737
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 69, # 5 p. 1734 - 1737
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 69, # 5 p. 1734 - 1737

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.87
  • LogP   1.3768
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 65632-62-4 sigma65632-62-4 manufacturer65632-62-4 price65632-62-4 structure65632-62-4 SDSbuy 65632-62-465632-62-4 supplier65632-62-4 uses65632-62-4 molecular weightprice of 65632-62-465632-62-4 chemical name formula of 65632-62-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label