2-Bromo-N-methoxy-N-methylisonicotinamide

Name: 2-Bromo-N-methoxy-N-methylisonicotinamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 656257-69-1
Cat. No. CS-0151365
Purity≥98%
MDL No.MFCD11847738

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-N-methoxy-N-methylisonicotinamide|CS-0151365

Structure of 656257-69-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 656257-69-1
Cat. No. CS-0151365
Purity ≥98%
MDL No. MFCD11847738
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉BrN₂O₂
Molecular Weight 245.07
Synonym(s) 2-BROMO-N-METHOXY-N-METHYLPYRIDINE-4-CARBOXAMIDE
SMILES CN(C(=O)C1=CC(=NC=C1)Br)OC

Description

2-Bromo-N-methoxy-N-methylisonicotinamide delivers a reactive bromo group positioned ortho to a tunable amide handle, enabling selective coupling in late-stage functionalization. The N-methoxy and N-methyl substituents enhance solubility and stabilize the amide against hydrolysis under standard conditions. This combination facilitates efficient incorporation into complex molecular architectures.

Application

2-Bromo-N-methoxy-N-methylisonicotinamide serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The bromo group facilitates C–C and C–heteroatom bond formation under standard conditions, while the N-methoxy-N-methyl amide moiety provides stability and favorable solubility. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing bioactive heterocyclic scaffolds in API development.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 42.43
LogP 1.4775
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

656257-69-1 sigma656257-69-1 manufacturer656257-69-1 price656257-69-1 structure656257-69-1 SDSbuy 656257-69-1656257-69-1 supplier656257-69-1 uses656257-69-1 molecular weightprice of 656257-69-1656257-69-1 chemical name formula of 656257-69-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-N-methoxy-N-methylisonicotinamide

CAS No. 656257-69-1

Recommended Products