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CS-W001157 4
Total: USD 88.00

2-(4-Pyrazol-1-ylphenyl)acetic acid

  • CAS No. 65476-24-6

  • Cat. No. CS-0060689
  • Molecule weight202.21
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Pyrazol-1-ylphenyl)acetic acid|CS-0060689

Structure of 65476-24-6

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General Information

  • CAS No. 65476-24-6
  • Cat. No. CS-0060689
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀N₂O₂
  • Molecular Weight 202.21
  • Synonym(s) [4-(1H-pyrazol-1-yl)phenyl]acetic acid
  • SMILES C1=CN(C2=CC=C(C=C2)CC(=O)O)N=C1

Synthesis

  • Route1
    • null|null
      66956-13-6
    • ~81%
    • 2-(4-Pyrazol-1-ylphenyl)acetic acid|CS-0060689
      65476-24-6

    References

    • ACADIA PHARMACEUTICALS INC. Patent: WO2004/808 A2, 2003 ; Location in patent: Page 87 ; WO 2004/000808 A2
  • Route2
    • Ethyl 4-(1H-pyrazol-1-yl)benzoate|CS-0313703
      143426-47-5
    • ~%
    • 2-(4-Pyrazol-1-ylphenyl)acetic acid|CS-0060689
      65476-24-6

    References

    • Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
  • Route3

    References

    • Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   1.4994
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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