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Structure of 65423-44-1
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2-(Diphenylphosphino)aniline features a diphenylphosphino group directly attached to an aniline scaffold, delivering a robust, electron-rich phosphine ligand. This structure enables efficient coordination in palladium-catalyzed cross-coupling reactions. The ortho-amine functionality enhances metal binding and offers potential for modular derivatization. Bench-stable under standard conditions, it serves as a reliable building block in catalytic system design.
2-(Diphenylphosphino)aniline serves as a versatile phosphine ligand in transition metal catalysis, enabling efficient cross-coupling reactions such as Suzuki-Miyaura and Heck transformations. Its ortho-phosphinoaniline structure provides strong coordination to palladium and nickel centers, enhancing catalyst stability and turnover. The molecule exhibits good bench stability and facilitates purification via standard chromatographic methods, making it well-suited for scalable synthetic applications in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: