Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2-(trifluoromethyl)benzoic acid

  • CAS No. 654-98-8

  • Cat. No. CS-W010441
  • Purity≥97%
  • MDL No.MFCD01631353

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-(trifluoromethyl)benzoic acid|CS-W010441

Structure of 654-98-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 654-98-8
  • Cat. No. CS-W010441
  • Purity ≥97%
  • MDL No. MFCD01631353
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄ClF₃O₂
  • Molecular Weight 224.56
  • Synonym(s) 5-Chlor-2-trifluormethyl-benzoesaeure
  • SMILES OC(=O)C1=C(C=CC(Cl)=C1)C(F)(F)F

Description

5-Chloro-2-(trifluoromethyl)benzoic acid features a strategically positioned trifluoromethyl group that enhances electron withdrawal and metabolic stability. The ortho-chloro substituent further modulates electronic properties, making this scaffold valuable for pharmaceutical intermediates and agrochemical development under standard conditions.

Application

5-Chloro-2-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, heterocycles, and bioactive scaffolds. Its orthogonal functional groups—chlorine and trifluoromethyl—facilitate palladium-catalyzed cross-couplings and electrophilic substitutions, while the carboxylic acid enables direct derivatization or salt formation. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it well-suited for high-throughput screening campaigns and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.057
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-2-(trifluoromethyl)benzoic acid sigma5-Chloro-2-(trifluoromethyl)benzoic acid manufacturer5-Chloro-2-(trifluoromethyl)benzoic acid price5-Chloro-2-(trifluoromethyl)benzoic acid structure5-Chloro-2-(trifluoromethyl)benzoic acid SDSbuy 5-Chloro-2-(trifluoromethyl)benzoic acid5-Chloro-2-(trifluoromethyl)benzoic acid supplier5-Chloro-2-(trifluoromethyl)benzoic acid uses5-Chloro-2-(trifluoromethyl)benzoic acid molecular weightprice of 5-Chloro-2-(trifluoromethyl)benzoic acid5-Chloro-2-(trifluoromethyl)benzoic acid chemical name formula of 5-Chloro-2-(trifluoromethyl)benzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label