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CS-W001157 4
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(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol

  • CAS No. 65355-00-2

  • Cat. No. CS-0031461
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol|CS-0031461

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General Information

  • CAS No. 65355-00-2
  • Cat. No. CS-0031461
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₂O₂
  • Molecular Weight 294.39
  • Synonym(s) (S)-(-)-5,5,6,6,7,7,8,8-Octahydro-1,1-bi-2-naphtol
  • SMILES OC1=CC=C2CCCCC2=[C@]1[C@]3=C(O)C=CC4=C3CCCC4

Description

(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol is a chiral bisphenol featuring a rigid, sterically defined scaffold with two hydroxyl groups in a cis-arrangement. This configuration enables high enantioselectivity in asymmetric synthesis and serves as a robust ligand scaffold for transition metal catalysis. The fully saturated naphthalene rings confer enhanced stability and solubility in organic media.

Application

(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol serves as a chiral auxiliary in asymmetric synthesis, enabling stereoselective transformations through its rigid binaphthyl framework. The compound exhibits excellent bench stability, facilitates efficient enantioselective functionalization, and functions reliably in catalytic asymmetric reactions. Its defined stereochemistry and robust structural integrity support predictable reactivity in the construction of complex chiral molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   4.5224
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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