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CS-W001157 4
Total: USD 88.00

N-Cyclopropyl-4-methylbenzenesulfonamide

  • CAS No. 65032-46-4

  • Cat. No. CS-0163611
  • Purity≥98%
  • MDL No.MFCD00551293
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-Cyclopropyl-4-methylbenzenesulfonamide|CS-0163611

Structure of 65032-46-4

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Description

N-Cyclopropyl-4-methylbenzenesulfonamide features a cyclopropyl group attached to the sulfonamide nitrogen, enhancing metabolic stability and lipophilicity. The para-methyl aryl sulfonamide scaffold provides robust electron donation and steric resilience. This compound integrates readily into bioactive scaffolds for kinase inhibition and medicinal chemistry screening under standard conditions.

Application

N-Cyclopropyl-4-methylbenzenesulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and process development. Its cyclopropyl amine moiety provides favorable metabolic stability and enhanced membrane permeability, while the para-methylbenzenesulfonamide group offers robust functional group tolerance and ease of purification. The compound facilitates diverse transformations in late-stage functionalization and enables efficient construction of biologically relevant heterocyclic scaffolds through standard coupling protocols.

General Information

  • CAS No. 65032-46-4
  • Cat. No. CS-0163611
  • Purity ≥98%
  • MDL No. MFCD00551293
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₂S
  • Molecular Weight 211.28
  • Synonym(s) None
  • SMILES O=S(C1=CC=C(C)C=C1)(NC2CC2)=O

Computational Chemistry Data

  • TPSA   46.17
  • LogP   1.43572
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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