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Structure of 65032-46-4
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N-Cyclopropyl-4-methylbenzenesulfonamide features a cyclopropyl group attached to the sulfonamide nitrogen, enhancing metabolic stability and lipophilicity. The para-methyl aryl sulfonamide scaffold provides robust electron donation and steric resilience. This compound integrates readily into bioactive scaffolds for kinase inhibition and medicinal chemistry screening under standard conditions.
N-Cyclopropyl-4-methylbenzenesulfonamide serves as a stable, bench-ready sulfonamide building block for medicinal chemistry and process development. Its cyclopropyl amine moiety provides favorable metabolic stability and enhanced membrane permeability, while the para-methylbenzenesulfonamide group offers robust functional group tolerance and ease of purification. The compound facilitates diverse transformations in late-stage functionalization and enables efficient construction of biologically relevant heterocyclic scaffolds through standard coupling protocols.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: