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CS-W001157 4
Total: USD 88.00

6-Bromo-1,8-naphthyridin-2-amine

  • CAS No. 64874-38-0

  • Cat. No. CS-W022447
  • Purity≥97%
  • MDL No.MFCD09909648

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1,8-naphthyridin-2-amine|CS-W022447

Structure of 64874-38-0

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General Information

  • CAS No. 64874-38-0
  • Cat. No. CS-W022447
  • Purity ≥97%
  • MDL No. MFCD09909648
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrN₃
  • Molecular Weight 224.06
  • Synonym(s) 6-Bromo-1,8-naphthyridin-2-amine, 2-Amino-6-bromo-1,8-diazanaphthalene
  • SMILES NC2=NC1=NC=C(C=C1C=C2)Br

Description

6-Bromo-1,8-naphthyridin-2-amine features a brominated naphthyridine core with a strategically positioned amine group, enabling direct incorporation into transition metal-catalyzed coupling reactions. The electron-deficient heterocyclic framework enhances reactivity in cross-coupling protocols, while the bench-stable nature simplifies handling and integration into synthetic sequences.

Application

6-Bromo-1,8-naphthyridin-2-amine serves as a versatile building block in medicinal chemistry and catalytic synthesis. The bromine and amine functionalities enable reliable cross-coupling reactions and direct functionalization, facilitating the construction of complex heterocyclic scaffolds. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for iterative synthesis workflows in drug discovery and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.9745
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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