Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,8-Naphthyridin-2-amine

  • CAS No. 15992-83-3

  • Cat. No. CS-W021294
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,8-Naphthyridin-2-amine|CS-W021294

Structure of 15992-83-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 15992-83-3
  • Cat. No. CS-W021294
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃
  • Molecular Weight 145.16
  • Synonym(s) 1,8-Naphthyridin-2(1H)-imine
  • SMILES NC1=NC2=NC=CC=C2C=C1

Description

1,8-Naphthyridin-2-amine delivers a rigid, electron-deficient heterocyclic scaffold ideal for constructing metal chelators and ligands in catalysis. This bench-stable, nitrogen-rich core integrates readily into coordination complexes, enhancing binding affinity through dual nitrogen donor sites positioned for optimal geometry.

Application

1,8-Naphthyridin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry and catalyst design. Its electron-deficient aromatic core enables robust metal coordination and facilitates C–H functionalization reactions. The pendant amine group provides a handle for derivatization via amide coupling or reductive amination, while the scaffold exhibits excellent bench stability and compatibility with standard synthetic protocols.

Synthesis

  • Route1

    References

    • Journal of Organic Chemistry, , vol. 46, # 10 p. 2134 - 2137
  • Route2

    References

    • LYCERA CORPORATION; AICHER, Thomas, Daniel; TOOGOOD, Peter, L.; HU, Xiao Patent: WO2013/169864 A2, 2013 ; Location in patent: Paragraph 00198 ;
  • Route3

    References

    • Wozniak, Marian; Skiba, Maria Polish Journal of Chemistry, 1981 , vol. 55, # 11 p. 2429 - 2438

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.212
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,8-Naphthyridin-2-amine sigma1,8-Naphthyridin-2-amine manufacturer1,8-Naphthyridin-2-amine price1,8-Naphthyridin-2-amine structure1,8-Naphthyridin-2-amine SDSbuy 1,8-Naphthyridin-2-amine1,8-Naphthyridin-2-amine supplier1,8-Naphthyridin-2-amine uses1,8-Naphthyridin-2-amine molecular weightprice of 1,8-Naphthyridin-2-amine1,8-Naphthyridin-2-amine chemical name formula of 1,8-Naphthyridin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label