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CS-W001157 4
Total: USD 88.00

1,2-Dibromo-4,5-difluorobenzene

  • CAS No. 64695-78-9

  • Cat. No. CS-W012363
  • Molecule weight271.89
  • Purity≥98%
  • MDL No.MFCD00009890

*For research and further manufacturing use only, not for direct human use.

1,2-Dibromo-4,5-difluorobenzene|CS-W012363

Structure of 64695-78-9

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General Information

  • CAS No. 64695-78-9
  • Cat. No. CS-W012363
  • Purity ≥98%
  • MDL No. MFCD00009890
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Br₂F₂
  • Molecular Weight 271.89
  • Synonym(s) 1,2-Dibromo-4,5-difl
  • SMILES FC1=C(F)C=C(Br)C(Br)=C1

Description

1,2-Dibromo-4,5-difluorobenzene has been used in the preparation of:2,2-dibromo-4,4,5,5-tetrafluorobiphenyl2-(2,3-dibromo-5,6-difluorophenyl)propan-2-ol

Application

1,2-Dibromo-4,5-difluorobenzene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromine atoms facilitate Suzuki, Stille, and Negishi couplings under mild conditions, while the fluorine substituents enhance metabolic stability and modulate electronic properties. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.

Synthesis

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    • In-stock
      1,2-Dibromo-4,5-difluorobenzene|CS-W012363
      64695-78-9
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      128259-74-5

    References

    • Bolton, Roger; Owen, Elaine S. E. Journal of Fluorine Chemistry, 1990 , vol. 46, # 3 p. 393 - 406
  • Route2
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      367-11-3
    • ~%
    • In-stock
      1,2-Dibromo-4,5-difluorobenzene|CS-W012363
      64695-78-9

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 42, # 6 p. 2001 - 2017

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.4898
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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