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Structure of 64574-21-6
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1H-Benzimidazole-4-carbonitrile is a bench-stable heterocyclic scaffold featuring a nitrile group at the 4-position, enabling direct functionalization in synthetic transformations. This electron-deficient aromatic system integrates readily into pharmaceutical intermediates and advanced materials, offering enhanced solubility and compatibility under standard reaction conditions.
1H-Benzimidazole-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its nitrile group provides a handle for downstream functionalization, while the benzimidazole core offers robust stability and favorable pharmacophoric properties. The compound exhibits excellent bench stability and compatibility with standard purification methods, facilitating efficient integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: