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Structure of 87189-16-0
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Potassium 2-bromo-2,2-difluoroacetate delivers a uniquely reactive trifluoromethylated synthon featuring a bromine atom adjacent to a stabilized carbanion. This bench-stable reagent facilitates efficient C–C bond formation in transition-metal-catalyzed coupling reactions and enables direct functionalization of electron-deficient substrates under mild conditions.
Potassium 2-bromo-2,2-difluoroacetate serves as a versatile synthon for introducing the CF₂Br group into organic frameworks. It facilitates nucleophilic substitution reactions with amines, thiols, and stabilized carbon nucleophiles under mild conditions. The compound exhibits good bench stability and enables efficient access to fluorinated building blocks relevant to medicinal chemistry and agrochemical synthesis. Its reactivity profile supports straightforward functionalization in multi-step sequences.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: