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CS-W001157 4
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Tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

  • CAS No. 645418-66-2

  • Cat. No. CS-0315718
  • Molecule weight276.37
  • Purity≥98%
  • MDL No.MFCD11518979

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate|CS-0315718

Structure of 645418-66-2

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General Information

  • CAS No. 645418-66-2
  • Cat. No. CS-0315718
  • Purity ≥98%
  • MDL No. MFCD11518979
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₄N₂O₂
  • Molecular Weight 276.37
  • Synonym(s) tert-Butyl 7-Amino-4,4-dimethyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CC2=CC(=CC=C2C(C)(C)C1)N

Synthesis

  • Route1
    • Tert-butyl 4,4-dimethyl-7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate|CS-0895372
      453560-80-0
    • ~%
    • Tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate|CS-0315718
      645418-66-2

    References

    • AMGEN INC Patent: WO2004/85425 A1, 2004 ; Location in patent: Page 135 ; WO 2004/085425 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   3.2971
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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