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CS-W001157 4
Total: USD 88.00

(S)-4-Methylisoxazolidin-4-ol hydrochloride

  • CAS No. 644970-79-6

  • Cat. No. CS-0379936
  • Purity≥95%
  • MDL No.MFCD31540079
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-4-Methylisoxazolidin-4-ol hydrochloride|CS-0379936

Structure of 644970-79-6

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Description

(S)-4-Methylisoxazolidin-4-ol hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a rigid isoxazolidine core. This configurationally stable scaffold integrates readily into complex molecular architectures, offering predictable stereocontrol in asymmetric synthesis. Its polar hydroxyl and protonated amine groups enhance solubility in aqueous and protic solvents, facilitating efficient downstream functionalization.

Application

(S)-4-Methylisoxazolidin-4-ol hydrochloride serves as a chiral building block for the synthesis of bioactive heterocycles and peptidomimetics. Its stable, bench-ready form facilitates straightforward incorporation into multistep syntheses, enabling efficient access to isoxazolidine-containing scaffolds via nucleophilic displacement or cycloaddition reactions. The compound exhibits excellent functional group tolerance and predictable stereochemical control in downstream transformations.

General Information

  • CAS No. 644970-79-6
  • Cat. No. CS-0379936
  • Purity ≥95%
  • MDL No. MFCD31540079
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₂
  • Molecular Weight 139.58
  • Synonym(s) None
  • SMILES C[C@@]1(CNOC1)O.Cl

Computational Chemistry Data

  • TPSA   41.49
  • LogP   -0.306
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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