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CS-W001157 4
Total: USD 88.00

5-Amino-1H-pyrazole-3-carboxylic acid

  • CAS No. 124004-31-5

  • Cat. No. CS-0054017
  • Molecule weight127.10
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Amino-1H-pyrazole-3-carboxylic acid|CS-0054017

Structure of 124004-31-5

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General Information

  • CAS No. 124004-31-5
  • Cat. No. CS-0054017
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O₂
  • Molecular Weight 127.10
  • Synonym(s) 5-Aminopyrazole-3-carboxylic acid
  • SMILES NC1=CC(=NN1)C(O)=O

Description

5-Amino-1H-pyrazole-3-carboxylic acid features a dual functional group motif: a primary amine and a carboxylic acid positioned at opposite ends of the pyrazole ring. This arrangement enables straightforward conjugation and derivatization in medicinal chemistry applications. The compound exhibits enhanced solubility in aqueous and polar organic solvents, facilitating use in solution-phase synthesis and biochemical assays.

Application

5-Amino-1H-pyrazole-3-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct access to pyrazole-based scaffolds prevalent in medicinal chemistry. Its dual functionality—amino and carboxylic acid groups—facilitates diverse derivatization via amide coupling, acylation, or cyclization reactions. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis and downstream functionalization in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   92
  • LogP   -0.3099
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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