Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-iodoaniline

  • CAS No. 64085-52-5

  • Cat. No. CS-W004813
  • Purity≥95%
  • MDL No.MFCD09753734

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-iodoaniline|CS-W004813

Structure of 64085-52-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 64085-52-5
  • Cat. No. CS-W004813
  • Purity ≥95%
  • MDL No. MFCD09753734
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrIN
  • Molecular Weight 297.92
  • Synonym(s) Benzenamine, 5-bromo-2-iodo-
  • SMILES NC1=CC(Br)=CC=C1I

Description

5-Bromo-2-iodoaniline delivers a dual halogenated aniline scaffold with orthogonal reactivity, enabling sequential cross-coupling strategies in complex molecule assembly. The para-bromo and ortho-iodo substituents facilitate selective Pd-catalyzed transformations under standard conditions, while the amine group provides a handle for derivatization. This compound exhibits bench-stable behavior and moisture-tolerant handling characteristics, simplifying integration into multi-step synthetic sequences.

Application

5-Bromo-2-iodoaniline serves as a versatile diarylated aniline building block for cross-coupling reactions and heterocycle synthesis. Its orthogonal halogen reactivity enables sequential functionalization, with the bromo group typically participating in palladium-catalyzed couplings while the iodo substituent offers high reactivity in Suzuki or Sonogashira transformations. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating integration into multi-step synthetic sequences for pharmaceutical and agrochemical intermediates.

Synthesis

  • Route1

    References

    • Heterocycles, , vol. 79, # C p. 805 - 820
  • Route2

    References

    • Chemical & Pharmaceutical Bulletin, , vol. 35, # 5 p. 1823 - 1828
  • Route3

    References

    • Chemical & Pharmaceutical Bulletin, , vol. 35, # 5 p. 1823 - 1828

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6359
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-iodoaniline sigma5-Bromo-2-iodoaniline manufacturer5-Bromo-2-iodoaniline price5-Bromo-2-iodoaniline structure5-Bromo-2-iodoaniline SDSbuy 5-Bromo-2-iodoaniline5-Bromo-2-iodoaniline supplier5-Bromo-2-iodoaniline uses5-Bromo-2-iodoaniline molecular weightprice of 5-Bromo-2-iodoaniline5-Bromo-2-iodoaniline chemical name formula of 5-Bromo-2-iodoaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label