Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-6-iodoaniline

  • CAS No. 84483-27-2

  • Cat. No. CS-0098697
  • Purity≥95%
  • MDL No.MFCD18391615

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-iodoaniline|CS-0098697

Structure of 84483-27-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 84483-27-2
  • Cat. No. CS-0098697
  • Purity ≥95%
  • MDL No. MFCD18391615
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrIN
  • Molecular Weight 297.92
  • Synonym(s) 2-bomo-6-iodoaniline
  • SMILES NC1=C(C=CC=C1Br)I

Description

2-Bromo-6-iodoaniline features dual halogen substituents at the ortho and para positions relative to the amino group, enabling selective cross-coupling reactions. This electron-deficient aryl halide integrates efficiently into Suzuki-Miyaura and Buchwald-Hartwig transformations under standard conditions. The molecule exhibits enhanced stability during catalytic processes and is compatible with palladium-based catalyst systems.

Application

2-Bromo-6-iodoaniline serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its orthogonal halogenation pattern facilitates sequential functionalization, while the amine group provides direct handle for derivatization. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Morrison, Matthew D.; Hanthorn, Jason J.; Pratt, Derek A. Organic Letters, 2009 , vol. 11, # 5 p. 1051 - 1054
  • Route2

    References

    • Roche, Didier; Prasad, Kapa; Repic, Oljan; Blacklock, Thomas J. Tetrahedron Letters, 2000 , vol. 41, # 13 p. 2083 - 2085
  • Route3
    • null|null
      615-36-1
    • ~%
    • In-stock
      2-Bromo-4-iodoaniline|CS-0041108
      29632-73-3
    • In-stock
      2-Bromo-6-iodoaniline|CS-0098697
      84483-27-2

    References

    • Shen, Hao; Vollhardt, K. Peter C. Synlett, 2012 , # 2 p. 208 - 214

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6359
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-6-iodoaniline sigma2-Bromo-6-iodoaniline manufacturer2-Bromo-6-iodoaniline price2-Bromo-6-iodoaniline structure2-Bromo-6-iodoaniline SDSbuy 2-Bromo-6-iodoaniline2-Bromo-6-iodoaniline supplier2-Bromo-6-iodoaniline uses2-Bromo-6-iodoaniline molecular weightprice of 2-Bromo-6-iodoaniline2-Bromo-6-iodoaniline chemical name formula of 2-Bromo-6-iodoaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label