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CS-W001157 4
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Glycochenodeoxycholic acid

  • CAS No. 640-79-9

  • Cat. No. CS-6319
  • Molecule weight449.62
  • Purity≥98%
  • MDL No.MFCD00271498

*For research and further manufacturing use only, not for direct human use.

Glycochenodeoxycholic acid|CS-6319

Structure of 640-79-9

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General Information

  • CAS No. 640-79-9
  • Cat. No. CS-6319
  • Purity ≥98%
  • MDL No. MFCD00271498
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₄₃NO₅
  • Molecular Weight 449.62
  • Synonym(s) Chenodeoxycholylglycine
  • SMILES C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCC(O)=O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@](C[C@H](O)CC4)([H])C[C@H]3O)C)([H])CC1

Description

Glycochenodeoxycholic acid integrates a glycine conjugate with a bile acid scaffold, enhancing solubility and membrane permeability. This derivative exhibits robust stability under physiological conditions and serves as a key intermediate in metabolic pathway studies and synthetic glycoconjugate development.

Application

Glycochenodeoxycholic acid serves as a key bile acid scaffold for studying hepatic transport, metabolic signaling, and drug delivery systems. Its glycoconjugated structure enhances solubility and stability in biological assays, while the C7 hydroxyl group enables site-specific derivatization. The molecule functions effectively in conjugation studies and as a building block for synthetic analogs targeting nuclear receptor modulation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   106.86
  • LogP   3.5941
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   6

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