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CS-W001157 4
Total: USD 88.00

Ethenesulfonamide

  • CAS No. 2386-58-5

  • Cat. No. CS-0091212
  • Purity≥97%
  • MDL No.MFCD00051751

*For research and further manufacturing use only, not for direct human use.

Ethenesulfonamide|CS-0091212

Structure of 2386-58-5

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General Information

  • CAS No. 2386-58-5
  • Cat. No. CS-0091212
  • Purity ≥97%
  • MDL No. MFCD00051751
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₅NO₂S
  • Molecular Weight 107.13
  • Synonym(s) JOXWSDNHLSQKCC-UHFFFAOYSA-N
  • SMILES C=CS(=O)(N)=O

Description

Ethenesulfonamide features a vinyl sulfonamide group enabling direct conjugation in bioconjugation workflows. The electron-deficient alkene facilitates Michael addition reactions with nucleophilic residues, offering a stable linkage under physiological conditions. This reactivity profile supports efficient labeling of proteins and peptides without requiring activation steps.

Application

Ethenesulfonamide serves as a versatile sulfonamide building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and bioactive molecules. Its reactive vinyl group facilitates conjugate additions, cycloadditions, and transition-metal-catalyzed couplings, while the sulfonamide moiety offers excellent stability and polarity for purification. This compound functions effectively in medicinal chemistry campaigns requiring functional group tolerance and bench-stable intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   -0.5816
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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