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CS-W001157 4
Total: USD 88.00

4-Chlorothieno[2,3-b]pyridine-5-carbonitrile

  • CAS No. 63873-61-0

  • Cat. No. CS-0084889
  • Purity≥97%
  • MDL No.MFCD08706210

*For research and further manufacturing use only, not for direct human use.

4-Chlorothieno[2,3-b]pyridine-5-carbonitrile|CS-0084889

Structure of 63873-61-0

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General Information

  • CAS No. 63873-61-0
  • Cat. No. CS-0084889
  • Purity ≥97%
  • MDL No. MFCD08706210
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₃ClN₂S
  • Molecular Weight 194.64
  • Synonym(s) 6-bromo-5-fluoro-1,3-dihydroindol-4-one
  • SMILES N#CC1=CN=C2C(C=CS2)=C1Cl

Synthesis

  • Route1
    • 4-Hydroxythieno[2,3-b]pyridine-5-carbonitrile|CS-0130305
      63873-60-9
    • ~77%
    • 4-Chlorothieno[2,3-b]pyridine-5-carbonitrile|CS-0084889
      63873-61-0

    References

    • Leal, Bruno; Afonso, Ilidio F.; Rodrigues, Carlos R.; Abreu, Paula A.; Garrett, Rafael; Pinheiro, Luiz Carlos S.; Azevedo, Alexandre R.; Borges, Julio C.; Vegi, Percilene F.; Santos, Claudio C.C.; da Silveira, Francisco C.A.; Cabral, Lucio M.; Frugulhetti, Izabel C.P.P.; Bernardino, Alice M.R.; Santos, Dilvani O.; Castro, Helena C. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 17 p. 8196 - 8204
  • Route2
    • null|null
      700844-20-8
    • ~%
    • 4-Chlorothieno[2,3-b]pyridine-5-carbonitrile|CS-0084889
      63873-61-0

    References

    • Boschelli, Diane H.; Wu, Biqi; Sosa, Ana Carolina Barrios; Durutlic, Haris; Ye, Fei; Raifeld, Yuri; Golas, Jennifer M.; Boschelli, Frank Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6666 - 6668
  • Route3
    • null|null
      108-77-0
    • null|null
      700844-20-8
    • ~%
    • 4-Chlorothieno[2,3-b]pyridine-5-carbonitrile|CS-0084889
      63873-61-0

    References

    • Wyeth Patent: US2004/242883 A1, 2004 ; US 20040242883 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   2.82138
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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