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CS-W001157 4
Total: USD 88.00

2-(1-((Benzyloxy)carbonyl)piperidin-4-yl)acetic acid

  • CAS No. 63845-28-3

  • Cat. No. CS-0041208
  • Purity≥97%
  • MDL No.MFCD02179001

*For research and further manufacturing use only, not for direct human use.

2-(1-((Benzyloxy)carbonyl)piperidin-4-yl)acetic acid|CS-0041208

Structure of 63845-28-3

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General Information

  • CAS No. 63845-28-3
  • Cat. No. CS-0041208
  • Purity ≥97%
  • MDL No. MFCD02179001
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₉NO₄
  • Molecular Weight 277.32
  • Synonym(s) None
  • SMILES O=C(O)CC1CCN(C(=O)OCC=2C=CC=CC2)CC1

Description

This piperidine-based scaffold features a benzyloxycarbonyl-protected amine and a pendant acetic acid group, enabling direct incorporation into peptide synthesis workflows. The Cbz moiety provides orthogonal protection, while the carboxylic acid serves as a reactive handle for coupling reactions under standard conditions.

Application

2-(1-((Benzyloxy)carbonyl)piperidin-4-yl)acetic acid serves as a versatile building block for the synthesis of piperidine-containing pharmaceuticals and bioactive heterocycles. The benzyl carbamate (Cbz) group provides orthogonal protection for the piperidine nitrogen, enabling selective deprotection during late-stage functionalization. The pendant acetic acid moiety facilitates conjugation via amide bond formation or metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard peptide and medicinal chemistry workflows make it ideal for modular library synthesis and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.5099
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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