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CS-W001157 4
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4-(Benzyloxy)aniline Lapatinib Impurity

  • CAS No. 6373-46-2

  • Cat. No. CS-0229076
  • Purity≥98%
  • MDL No.MFCD00025318

*For research and further manufacturing use only, not for direct human use.

4-(Benzyloxy)aniline Lapatinib Impurity|CS-0229076

Structure of 6373-46-2

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General Information

  • CAS No. 6373-46-2
  • Cat. No. CS-0229076
  • Purity ≥98%
  • MDL No. MFCD00025318
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃NO
  • Molecular Weight 199.25
  • Synonym(s) 4-Benzyloxyaniline
  • SMILES NC1=CC=C(OCC2=CC=CC=C2)C=C1

Synthesis

  • Route1

    References

    • Vernekar, Amit A.; Patil, Sagar; Bhat, Chinmay; Tilve, Santosh G. RSC Advances, 2013 , vol. 3, # 32 p. 13243 - 13250
  • Route2
    • null|null
      852668-28-1
    • ~43%
    • 4-(Benzyloxy)aniline Lapatinib Impurity|CS-0229076
      6373-46-2

    References

    • AMBIT BIOSCIENCES CORPORATION Patent: WO2005/48948 A2, 2005 ; Location in patent: Page/Page column 168 ;
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 71, # 5 p. 2196 - 2199

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.8478
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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