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CS-W001157 4
Total: USD 88.00

2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid

  • CAS No. 6326-83-6

  • Cat. No. CS-0110494
  • Purity≥97%
  • MDL No.MFCD00004357

*For research and further manufacturing use only, not for direct human use.

2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid|CS-0110494

Structure of 6326-83-6

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General Information

  • CAS No. 6326-83-6
  • Cat. No. CS-0110494
  • Purity ≥97%
  • MDL No. MFCD00004357
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆O₄S₃
  • Molecular Weight 226.29
  • Synonym(s) Trithiocarbonic Acid Bis(carboxymethyl) Ester
  • SMILES S=C(SCC(O)=O)SCC(O)=O

Description

This thiocarbonyl-bridged diacid features a rigid, sulfur-rich scaffold that enhances metal coordination and solubility in polar solvents. The bifunctional carboxylic acid groups enable robust conjugation in chelation chemistry, while the thioether linkages confer improved stability under oxidative conditions.

Application

2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid serves as a versatile bifunctional building block for constructing sulfur-containing heterocycles and peptide mimetics. Its dual thiol and carboxylic acid functionalities enable efficient conjugation via disulfide formation or amide coupling, offering robust stability and compatibility with standard synthetic protocols. Functions effectively in modular synthesis of bioactive scaffolds requiring orthogonal reactivity.

Synthesis

  • Route1
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      75-15-0
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      79-11-8
    • ~%
    • In-stock
      2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid|CS-0110494
      6326-83-6

    References

    • Scientia Pharmaceutica, , vol. 67, # 4 p. 227 - 230
  • Route2
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      6310-26-5
    • ~%
    • In-stock
      2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid|CS-0110494
      6326-83-6

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 99, p. 56,57, 59
  • Route3
    • null|null
      108748-13-6
    • ~%
    • In-stock
      2,2'-(Thiocarbonylbis(sulfanediyl))diacetic acid|CS-0110494
      6326-83-6

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. 11, p. 284 - 308

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.9069
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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