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CS-W001157 4
Total: USD 88.00

6-Aminonaphthalene-1,3-disulfonic acid

  • CAS No. 118-33-2

  • Cat. No. CS-0367308
  • Purity≥95%
  • MDL No.MFCD00021513

*For research and further manufacturing use only, not for direct human use.

6-Aminonaphthalene-1,3-disulfonic acid|CS-0367308

Structure of 118-33-2

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General Information

  • CAS No. 118-33-2
  • Cat. No. CS-0367308
  • Purity ≥95%
  • MDL No. MFCD00021513
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO₆S₂
  • Molecular Weight 303.31
  • Synonym(s) 6-aminonaphthalene-1,3-disulphonic acid
  • SMILES C1=CC2=C(C=C(C=C2C=C1N)S(=O)(=O)O)S(=O)(=O)O

Description

6-Aminonaphthalene-1,3-disulfonic acid features a naphthalene core bearing two sulfonic acid groups and a primary amine at the 6-position, offering high water solubility and robust stability under standard conditions. The electron-rich aromatic system enables efficient coupling reactions, while the ortho-sulfonate arrangement enhances solvation and reactivity in aqueous media. This structure supports use in dye synthesis, polymer functionalization, and bioconjugation workflows requiring precise charge distribution and hydrophilic character.

Application

6-Aminonaphthalene-1,3-disulfonic acid serves as a versatile building block for sulfonated aromatic systems, enabling efficient access to dyes, ion-exchange resins, and functionalized heterocycles. Its ortho-disulfonic acid groups provide enhanced water solubility and stability, while the 6-amino functionality facilitates direct coupling reactions, including diazotization and electrophilic substitution. The compound exhibits excellent bench stability and simplifies purification in aqueous media, making it well-suited for scalable synthesis in industrial and process chemistry applications.

Synthesis

  • Route1
    • null|null
      81-16-3
    • ~0%
    • In-stock
      6-Aminonaphthalene-1,3-disulfonic acid|CS-0367308
      118-33-2
    • 7-Amino-1,3-naphthalenedisulfonic acid|CS-0645562
      86-65-7

    References

    • American Cyanamid Company Patent: US3979445 A1, 1976 ;
  • Route2

    References

    • Chem. News J. Ind. Sci., , vol. 62, p. 163
  • Route3
    • null|null
      91-59-8
    • ~%
    • In-stock
      6-Aminonaphthalene-1,3-disulfonic acid|CS-0367308
      118-33-2
    • 7-Amino-1,3-naphthalenedisulfonic acid|CS-0645562
      86-65-7

    References

    • Helvetica Chimica Acta, , vol. 6, p. 1147,1149 Grundlegende Operationen der Farbenchemie, 5. Aufl. <Wien 1943>, S. 197

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   134.76
  • LogP   0.9154
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   2

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