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CS-W001157 4
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Methyl 3-(3-chlorophenyl)-3-oxopropanoate

  • CAS No. 632327-19-6

  • Cat. No. CS-0046986
  • Purity≥97%
  • MDL No.MFCD03424772
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-(3-chlorophenyl)-3-oxopropanoate|CS-0046986

Structure of 632327-19-6

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Description

Methyl 3-(3-chlorophenyl)-3-oxopropanoate features a conjugated enone system flanked by a chlorinated aromatic ring and an ester group, enabling direct participation in Michael additions and Claisen condensations. This bench-stable reagent integrates readily into synthetic sequences requiring electrophilic aryl ketone surrogates.

Application

Methyl 3-(3-chlorophenyl)-3-oxopropanoate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted indoles and related scaffolds via cyclization reactions. The α,β-unsaturated ketone functionality supports Michael additions and condensation cascades, while the ester group permits further derivatization. Bench-stable and readily purified by column chromatography, it functions reliably in multistep sequences requiring functional group tolerance and predictable reactivity.

General Information

  • CAS No. 632327-19-6
  • Cat. No. CS-0046986
  • Purity ≥97%
  • MDL No. MFCD03424772
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉ClO₃
  • Molecular Weight None
  • Synonym(s) Methyl3-(3-chlorophenyl)-3-oxopropanoate
  • SMILES O=C(CC(OC)=O)C1=CC(Cl)=CC=C1

Computational Chemistry Data

  • TPSA   43.37
  • LogP   2.0858
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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