4-Chloro-2,6-dimethoxypyrimidine

Name: 4-Chloro-2,6-dimethoxypyrimidine
Brand: ChemScene
Availability: InStock
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CAS No. 6320-15-6
Cat. No. CS-0137521
Purity≥98%
MDL No.MFCD00006068

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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4-Chloro-2,6-dimethoxypyrimidine|CS-0137521

Structure of 6320-15-6

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Description

4-Chloro-2,6-dimethoxypyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, featuring two methoxy groups that enhance solubility and modulate electronic properties. The chlorine substituent enables efficient coupling reactions, facilitating the synthesis of advanced pharmaceutical intermediates under standard conditions.

Application

4-Chloro-2,6-dimethoxypyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of pyrimidine-based scaffolds. Its chloro group facilitates nucleophilic substitution reactions under mild conditions, while the dimethoxy substituents enhance solubility and provide orthogonal reactivity. The compound exhibits excellent bench stability and is compatible with standard coupling protocols, making it ideal for modular synthesis workflows.

General Information

CAS No. 6320-15-6
Cat. No. CS-0137521
Purity ≥98%
MDL No. MFCD00006068
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇ClN₂O₂
Molecular Weight 174.58
Synonym(s) 2,4-DIMETHOXY-6-CHLOROPYRIMIDINE
SMILES COC1=CC(Cl)=NC(OC)=N1

Computational Chemistry Data

TPSA 44.24
LogP 1.1472
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

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4-Chloro-2,6-dimethoxypyrimidine

CAS No. 6320-15-6

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