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CS-W001157 4
Total: USD 88.00

Aniline, 3,4-dimethoxy- 7CI,8CI

  • CAS No. 6315-89-5

  • Cat. No. CS-W019949
  • Purity≥97%
  • MDL No.MFCD00008394

*For research and further manufacturing use only, not for direct human use.

Aniline, 3,4-dimethoxy- 7CI,8CI|CS-W019949

Structure of 6315-89-5

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General Information

  • CAS No. 6315-89-5
  • Cat. No. CS-W019949
  • Purity ≥97%
  • MDL No. MFCD00008394
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₂
  • Molecular Weight 153.18
  • Synonym(s) 2-Methoxy-4-aminoanisole; 3,4-Bis(methoxy)aniline; 4-Aminoveratrole; 3,4-Dimethoxyaniline
  • SMILES NC1=CC=C(OC)C(OC)=C1

Description

3,4-Dimethoxyaniline features two methoxy groups flanking the amino functionality, enhancing electron density and solubility in organic media. This ortho-dimethoxy substitution pattern stabilizes the amine against oxidation while enabling direct incorporation into coupling reactions. The molecule serves as a key building block for pharmaceutical intermediates and functional dyes, offering improved reactivity in nucleophilic aromatic substitution processes under mild conditions.

Application

3,4-Dimethoxyaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted anilines via standard coupling reactions. Its ortho-dimethoxy substitution enhances electron density at the aromatic ring, facilitating electrophilic functionalization and improving solubility in polar solvents. The compound exhibits good bench stability and is compatible with common protecting group strategies, allowing straightforward incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302+H312
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.286
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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