2-Methoxy-6-methylpyridine

Name: 2-Methoxy-6-methylpyridine
Brand: ChemScene
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CAS No. 63071-03-4
Cat. No. CS-W003150
Purity≥98%
MDL No.MFCD04112507

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 63071-03-4

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Description

2-Methoxy-6-methylpyridine is a bench-stable, electron-rich heterocycle featuring a methoxy group at the 2-position and a methyl substituent at the 6-position. This combination enhances solubility and directs electrophilic substitution selectively. The compound serves as a key scaffold in medicinal chemistry and catalyst design, offering predictable reactivity under standard conditions.

Application

2-Methoxy-6-methylpyridine serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds through electrophilic substitution and transition-metal-catalyzed coupling reactions. Its ortho-substituted structure provides enhanced stability and predictable regiochemistry, while the methoxy and methyl groups offer complementary functional handles for further derivatization. The compound exhibits excellent bench stability and is readily purified by distillation or chromatography, making it well-suited for scalable synthesis and API development workflows.

General Information

CAS No. 63071-03-4
Cat. No. CS-W003150
Purity ≥98%
MDL No. MFCD04112507
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉NO
Molecular Weight None
Synonym(s) 6-Methoxy-2-picoline; 2-Methoxy-6-methylpyridine
SMILES CC1=NC(OC)=CC=C1

Computational Chemistry Data

TPSA 22.12
LogP 1.39862
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

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Signal Word : N/A	UN#: N/A
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Hazard Statements : N/A
Precautionary Statements : N/A

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2-Methoxy-6-methylpyridine

CAS No. 63071-03-4

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