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CS-W001157 4
Total: USD 88.00

Quinoxalin-6-amine Brimonidine Impurity

  • CAS No. 6298-37-9

  • Cat. No. CS-0229719
  • Purity≥98%
  • MDL No.MFCD00462821

*For research and further manufacturing use only, not for direct human use.

Quinoxalin-6-amine Brimonidine Impurity|CS-0229719

Structure of 6298-37-9

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General Information

  • CAS No. 6298-37-9
  • Cat. No. CS-0229719
  • Purity ≥98%
  • MDL No. MFCD00462821
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃
  • Molecular Weight 145.17
  • Synonym(s) None
  • SMILES N1=CC=NC2=CC(N)=CC=C12

Synthesis

  • Route1

    References

    • Sunovion Pharmaceuticals Inc. Patent: US2012/178748 A1, 2012 ; Location in patent: Page/Page column 43 ; US 20120178748 A1
  • Route2
    • Benzene-1,2,4-triaminedihydrochloride|CS-0171059
      615-47-4
    • ~87%
    • Quinoxalin-6-amine Brimonidine Impurity|CS-0229719
      6298-37-9

    References

    • Allergan, Inc. Patent: US5077292 A1, 1991 ; Title/Abstract Full Text Show Details Allergan Patent: US5552403 A1, 1996 ; US 5552403 A Title/Abstract Full Text Show Details Allergan, Inc. Patent: US5231096 A1, 1993 ; US 5231096 A Title/Abstract Full Text Show Details Allergan, Inc. Patent: US5021416 A1, 1991 ;
  • Route3

    References

    • Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L. Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.212
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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