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CS-W001157 4
Total: USD 88.00

3-Methoxypyrrolidine

  • CAS No. 62848-20-8

  • Cat. No. CS-0039937
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methoxypyrrolidine|CS-0039937

Structure of 62848-20-8

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General Information

  • CAS No. 62848-20-8
  • Cat. No. CS-0039937
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) 3-methoxy-pyrrolidine
  • SMILES COC1CNCC1

Description

3-Methoxypyrrolidine is a nitrogen-containing heterocycle featuring a methoxy group at the 3-position, offering enhanced solubility and modulated basicity. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for optimizing pharmacokinetic profiles.

Application

3-Methoxypyrrolidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of diverse nitrogen-containing scaffolds. Its methoxy group enhances solubility and modulates basicity, while the pyrrolidine core provides a rigid, bioactive framework. The compound exhibits excellent bench stability, tolerates a range of functional groups, and participates reliably in standard amine coupling, alkylation, and reductive amination protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   -0.0053
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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