1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpyrrolidine

Name: 1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpyrrolidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 627528-96-5
Cat. No. CS-0086852
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpyrrolidine|CS-0086852

Structure of 627528-96-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 627528-96-5
Cat. No. CS-0086852
Purity ≥97%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₀NO₂P
Molecular Weight 385.39
Synonym(s) 1-(11bS)-dinaphtho[2,1-d
SMILES C12=CC=CC=C1C=CC3=[C@]2[C@]4=C(C=CC=C5)C5=CC=C4OP(N6CCCC6)O3

Description

This chiral dioxaphosphepine-pyrrolidine moiety integrates a rigid, electron-deficient phosphorus heterocycle with a pyrrolidine nitrogen, enabling precise stereocontrol in asymmetric synthesis. The 11bS configuration ensures predictable diastereoselectivity in transition-metal-catalyzed transformations, while the fused naphthalene units enhance stability and π-stacking potential.

Application

1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpyrrolidine serves as a stereochemically defined phosphine ligand that facilitates transition-metal-catalyzed cross-coupling reactions. Its rigid, polycyclic backbone enhances thermal stability and electron-donating capacity, enabling efficient palladium-catalyzed C–C and C–heteroatom bond formations under mild conditions. The structure exhibits robust functional group tolerance and simplifies purification due to low volatility and high bench stability, making it suitable for scalable synthesis and process development in medicinal chemistry workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.52
LogP 7.3282
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Key Words

627528-96-5 sigma627528-96-5 manufacturer627528-96-5 price627528-96-5 structure627528-96-5 SDSbuy 627528-96-5627528-96-5 supplier627528-96-5 uses627528-96-5 molecular weightprice of 627528-96-5627528-96-5 chemical name formula of 627528-96-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(11bS)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpyrrolidine

CAS No. 627528-96-5

Recommended Products