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CS-W001157 4
Total: USD 88.00

(11bS)​-N,​N-​Dipropyl-dinaphtho[2,​1-​d:1',​2'-​f]​[1,​3,​2]​dioxaphosphepin-​4-​amine

  • CAS No. 802902-36-9

  • Cat. No. CS-0062237
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(11bS)​-N,​N-​Dipropyl-dinaphtho[2,​1-​d:1',​2'-​f]​[1,​3,​2]​dioxaphosphepin-​4-​amine|CS-0062237

Structure of 802902-36-9

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General Information

  • CAS No. 802902-36-9
  • Cat. No. CS-0062237
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₆NO₂P
  • Molecular Weight 415.46
  • Synonym(s) 3,4-a']dinaphthalen-4-yl)dipropylaMine
  • SMILES CCCN(CCC)P1OC2=[C@]([C@]3=C(C=CC=C4)C4=CC=C3O1)C5=C(C=CC=C5)C=C2

Description

This dipropyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine features a rigid, electron-rich phosphine scaffold with enhanced steric protection. The (11bS) stereochemistry ensures predictable reactivity in asymmetric catalysis, while the N,N-dipropyl substitution improves solubility and stability under ambient conditions. Ideal for transition-metal-catalyzed transformations requiring robust, chiral ligand performance.

Application

(11bS)-N,N-Dipropyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine serves as a stereochemically defined phosphine ligand, enabling efficient transition-metal-catalyzed cross-coupling reactions. Its rigid, chiral dioxaphosphepin scaffold provides excellent configurational stability and enhances catalytic performance in palladium- and nickel-mediated transformations. The dipropyl substitution improves solubility and functional group tolerance, facilitating straightforward purification and broad applicability in synthetic workflows requiring high enantioselectivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.52
  • LogP   8.3544
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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