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CS-W001157 4
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1,8-Dibromo-3,6-di-tert-butyl-9H-carbazole

  • CAS No. 625385-37-7

  • Cat. No. CS-0528794
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,8-Dibromo-3,6-di-tert-butyl-9H-carbazole|CS-0528794

Structure of 625385-37-7

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General Information

  • CAS No. 625385-37-7
  • Cat. No. CS-0528794
  • Purity ≥98%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₃Br₂N
  • Molecular Weight 437.21
  • Synonym(s) 1,8-Dibromo-3,6-bis(2-methyl-2-propanyl)-9H-carbazole
  • SMILES CC(C1=CC2=C(NC3=C2C=C(C(C)(C)C)C=C3Br)C(Br)=C1)(C)C

Description

1,8-Dibromo-3,6-di-tert-butyl-9H-carbazole features two bromine atoms at the 1 and 8 positions of the carbazole core, flanked by bulky tert-butyl groups at the 3 and 6 positions. This steric shielding enhances stability and facilitates controlled cross-coupling reactions in synthetic applications. The electron-rich framework supports efficient metal-catalyzed transformations.

Application

1,8-Dibromo-3,6-di-tert-butyl-9H-carbazole serves as a sterically hindered building block for the synthesis of functionalized carbazole scaffolds. The bromine atoms enable palladium-catalyzed cross-coupling reactions with broad functional group tolerance, while the bulky tert-butyl groups enhance solution stability and reduce undesired side reactions. This compound functions effectively in the construction of advanced materials and pharmaceutical intermediates requiring regioselective derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   7.4411
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

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