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Structure of 1829-28-3
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Ethyl 2-iodobenzoate delivers a reactive iodine handle ortho to an ester group, enabling direct functionalization in cross-coupling reactions. This bench-stable aryl iodide integrates readily into Suzuki, Stille, and Negishi transformations, offering predictable reactivity with minimal side processes. The ester moiety provides polarity for handling and purification.
Ethyl 2-iodobenzoate serves as a versatile aryl iodide building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation. Its ortho-iodine substitution facilitates selective functionalization under palladium or nickel catalysis, while the ester group provides compatibility with standard synthetic workflows. Bench-stable and readily purified by recrystallization, it functions reliably in Suzuki, Stille, and Negishi coupling protocols for the construction of biaryl and heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: