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Structure of 625120-14-1
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5-(Trifluoromethyl)isoxazole-3-carboxylic acid features a trifluoromethyl group at the 5-position, enhancing electron-withdrawing character and metabolic stability. This isoxazole scaffold provides rigidity and polarity, ideal for incorporating into bioactive molecules. The carboxylic acid moiety enables direct conjugation or salt formation, facilitating solubility and further derivatization in medicinal chemistry campaigns.
5-(Trifluoromethyl)isoxazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates amide formation and conjugation. The isoxazole core provides a rigid, electron-deficient scaffold compatible with diverse synthetic transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: