Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(Trifluoromethyl)isoxazole-3-carboxylic acid

  • CAS No. 625120-14-1

  • Cat. No. CS-0434090
  • Purity≥97%
  • MDL No.MFCD20658789

*For research and further manufacturing use only, not for direct human use.

5-(Trifluoromethyl)isoxazole-3-carboxylic acid|CS-0434090

Structure of 625120-14-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 625120-14-1
  • Cat. No. CS-0434090
  • Purity ≥97%
  • MDL No. MFCD20658789
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂F₃NO₃
  • Molecular Weight 181.07
  • Synonym(s) 5-(Trifluoromethyl)-1,2-oxazole-3-carboxylic acid
  • SMILES O=C(C1=NOC(C(F)(F)F)=C1)O

Description

5-(Trifluoromethyl)isoxazole-3-carboxylic acid features a trifluoromethyl group at the 5-position, enhancing electron-withdrawing character and metabolic stability. This isoxazole scaffold provides rigidity and polarity, ideal for incorporating into bioactive molecules. The carboxylic acid moiety enables direct conjugation or salt formation, facilitating solubility and further derivatization in medicinal chemistry campaigns.

Application

5-(Trifluoromethyl)isoxazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates amide formation and conjugation. The isoxazole core provides a rigid, electron-deficient scaffold compatible with diverse synthetic transformations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.33
  • LogP   1.3916
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 625120-14-1 sigma625120-14-1 manufacturer625120-14-1 price625120-14-1 structure625120-14-1 SDSbuy 625120-14-1625120-14-1 supplier625120-14-1 uses625120-14-1 molecular weightprice of 625120-14-1625120-14-1 chemical name formula of 625120-14-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label