Lot numbers can be found on the outside label of a product:
Methyl 6-bromoquinoline-2-carboxylate
-
CAS No. 623583-88-0
- Cat. No. CS-0099701
- Purity≥97%
- MDL No.MFCD08436465
*For research and further manufacturing use only, not for direct human use.
Structure of 623583-88-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 623583-88-0
- Cat. No. CS-0099701
- Purity ≥97%
- MDL No. MFCD08436465
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₈BrNO₂
- Molecular Weight 266.09
- Synonym(s) methyl 2-bromoquinoline-6-carboxylate
- SMILES O=C(C1=NC2=CC=C(Br)C=C2C=C1)OC
Description
Methyl 6-bromoquinoline-2-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a bromine atom at the 6-position and a methyl carboxylate group at the 2-position. This configuration enables direct functionalization via palladium-catalyzed cross-coupling, facilitating rapid access to complex quinoline derivatives in medicinal chemistry and materials synthesis.
Application
Methyl 6-bromoquinoline-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo and ester functionalities. The molecule exhibits excellent bench stability and facilitates efficient functionalization at the 6-position, supporting the construction of complex quinoline-based scaffolds relevant to medicinal chemistry and materials science.
Synthesis
-
Route1
-
67-56-1 -
In-stock
65148-10-9 - ~85%
-
In-stock
623583-88-0
References
-
SmithKline Beecham Corporation Patent: US2008/96921 A1, 2008 ; Location in patent: Page/Page column 32 ;
-
-
Route2
-
511230-72-1 - ~%
-
In-stock
623583-88-0
References
-
Hulme, Christopher; Ncube, Mghele Vellah; Norman, Mark H.; Ognyanov, Vassil I.; Pettus, Liping H.; Wang, Xianghong; Zhu, Jiawang Patent: US2005/165049 A1, 2005 ; Location in patent: Page/Page column 22 ; US 20050165049 A1
-
-
Route3
-
In-stock
877-42-9 - ~%
-
In-stock
623583-88-0
References
-
MERCK SHARP and DOHME CORP.; LIN, Linus; SOLL, Richard; DONG, Jingchao; WU, Hao; SUZUKI, Takao; HU, Bin; LIU, Dejun; HAO, Jinglai; XU, Ming Patent: WO2011/127643 A1, 2011 ; WO 2011/127643 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 39.19
- LogP 2.7839
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 6-bromoquinoline-2-carboxylate sigmaMethyl 6-bromoquinoline-2-carboxylate manufacturerMethyl 6-bromoquinoline-2-carboxylate priceMethyl 6-bromoquinoline-2-carboxylate structureMethyl 6-bromoquinoline-2-carboxylate SDSbuy Methyl 6-bromoquinoline-2-carboxylateMethyl 6-bromoquinoline-2-carboxylate supplierMethyl 6-bromoquinoline-2-carboxylate usesMethyl 6-bromoquinoline-2-carboxylate molecular weightprice of Methyl 6-bromoquinoline-2-carboxylateMethyl 6-bromoquinoline-2-carboxylate chemical name formula of Methyl 6-bromoquinoline-2-carboxylate