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Structure of 111851-98-0
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1-Ethyl-1H-imidazole-2-carbaldehyde features a reactive aldehyde group flanked by an electron-rich imidazole ring and an ethyl substituent, enabling efficient coupling in transition-metal-catalyzed transformations. This bench-stable reagent integrates readily into heterocyclic scaffolds, offering enhanced solubility and compatibility in synthetic workflows.
1-Ethyl-1H-imidazole-2-carbaldehyde serves as a versatile building block for imidazole-based heterocycles, enabling efficient access to bioactive scaffolds through nucleophilic addition and condensation reactions. The aldehyde functionality facilitates direct coupling with amines, hydrazines, and other nucleophiles under mild conditions, while the ethyl substituent enhances solubility and stability in common organic solvents. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for medicinal chemistry campaigns and combinatorial synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: