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CS-W001157 4
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2,3-Thiophene-dicarbaldehyde

  • CAS No. 932-41-2

  • Cat. No. CS-W014359
  • Purity≥98%
  • MDL No.MFCD00209616

*For research and further manufacturing use only, not for direct human use.

2,3-Thiophene-dicarbaldehyde|CS-W014359

Structure of 932-41-2

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General Information

  • CAS No. 932-41-2
  • Cat. No. CS-W014359
  • Purity ≥98%
  • MDL No. MFCD00209616
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄O₂S
  • Molecular Weight 140.16
  • Synonym(s) 2,3-Thiophenedicarboxaldehyde
  • SMILES O=CC1=C(C=O)C=CS1

Description

2,3-Thiophene-dicarbaldehyde features a rigid, electron-deficient thiophene core with two aldehyde groups positioned at adjacent ring carbons. This bifunctional scaffold enables direct coupling in cross-coupling reactions and facilitates the construction of complex heteroaromatic architectures under mild conditions. The molecule exhibits enhanced stability compared to analogous furan-based dicarbonyls, offering improved handling and reactivity control in synthetic workflows.

Application

2,3-Thiophene-dicarbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of complex scaffolds through classic carbonyl transformations. Its dual aldehyde functionality offers orthogonal reactivity for sequential coupling, condensation, or cyclization processes. The molecule exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • Thiophene-2,3-diyldimethanol|CS-0444689
      13250-85-6
    • ~%
    • In-stock
      2,3-Thiophene-dicarbaldehyde|CS-W014359
      932-41-2

    References

    • Tetrahedron, , vol. 67, # 31 p. 5582 - 5589

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   1.3731
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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