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Structure of 62290-40-8
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4-((4-Chlorobenzyl)oxy)benzoic acid features a para-chlorinated benzyl ether linkage flanking a carboxylic acid group, enabling direct integration into bioconjugation workflows. The electron-withdrawing chloro substituent enhances electrophilicity at the aromatic ring, facilitating coupling reactions under mild conditions. This scaffold combines stability with predictable reactivity, making it suitable for synthesizing targeted probes and functionalized intermediates in medicinal chemistry.
4-((4-Chlorobenzyl)oxy)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard esterification, amidation, and Suzuki-Miyaura coupling reactions. Its ortho-substituted aryl ether functionality offers enhanced metabolic stability, while the carboxylic acid group facilitates conjugation and derivatization. The compound exhibits excellent bench stability and is compatible with common purification methods, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P340-P362-P403-P405-P501
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Lot numbers can be found on the outside label of a product: