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CS-W001157 4
Total: USD 88.00

N-Benzylidenemethanamine

  • CAS No. 622-29-7

  • Cat. No. CS-0151232
  • Purity≥96%
  • MDL No.MFCD00008294

*For research and further manufacturing use only, not for direct human use.

N-Benzylidenemethanamine|CS-0151232

Structure of 622-29-7

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General Information

  • CAS No. 622-29-7
  • Cat. No. CS-0151232
  • Purity ≥96%
  • MDL No. MFCD00008294
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉N
  • Molecular Weight 119.16
  • Synonym(s) N-Benzylidenemethylamine
  • SMILES CN=CC1=CC=CC=C1

Description

N-Benzylidenemethanamine features a conjugated imine linkage between benzylidene and methylamino moieties, enabling its use as a key intermediate in heterocyclic synthesis. This bench-stable compound integrates readily into multistep transformations, offering high reactivity in nucleophilic addition and condensation reactions under mild conditions.

Application

N-Benzylidenemethanamine serves as a versatile enamine building block in synthetic organic chemistry, enabling efficient Mannich-type reactions and heterocycle construction. Its imine functionality facilitates nucleophilic addition and subsequent cyclization under mild conditions, offering reliable access to nitrogen-containing scaffolds. The compound exhibits good bench stability and is compatible with common functional groups, simplifying purification and integration into multi-step syntheses.

Synthesis

  • Route1
    • null|null
      593-51-1
    • null|null
      100-52-7
    • ~85%
    • In-stock
      N-Benzylidenemethanamine|CS-0151232
      622-29-7

    References

    • Radulovic, Niko S.; Miltojevic, Ana B.; Vukicevic, Rastko D. Comptes Rendus Chimie, 2013 , vol. 16, # 3 p. 257 - 270
  • Route2

    References

    • Neumann, Ronny; Levin, Michal Journal of Organic Chemistry, 1991 , vol. 56, # 19 p. 5707 - 5710
  • Route3
    • null|null
      100-52-7
    • null|null
      74-89-5
    • ~97%
    • In-stock
      N-Benzylidenemethanamine|CS-0151232
      622-29-7

    References

    • Baldridge, Anthony; Kowalik, Janusz; Tolbert, Laren M. Synthesis, 2010 , # 14 art. no. M06809SS, p. 2424 - 2436

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.36
  • LogP   1.7353
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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