Lot numbers can be found on the outside label of a product:
Isovanillin
-
CAS No. 621-59-0
- Cat. No. CS-W009023
- Purity≥98%
- MDL No.MFCD00003369
*For research and further manufacturing use only, not for direct human use.
Structure of 621-59-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 621-59-0
- Cat. No. CS-W009023
- Purity ≥98%
- MDL No. MFCD00003369
- Storage 4°C, protect from light, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₈O₃
- Molecular Weight None
- Synonym(s) 3-Hydroxy-4-methoxybenzaldehyde
- SMILES O=CC1=CC=C(OC)C(O)=C1
Description
3-Hydroxy-4-methoxybenzaldehyde on condensation with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide yields Schiff-bases. It undergoes condensation reaction with1-azabicyclo[2.2.2]octan-3-one to give (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one.3-Hydroxy-4-methoxybenzaldehyde was used as starting reagent during the two-step stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein synthesis.
Application
Isovanillin serves as a versatile phenolic aldehyde building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and natural product analogs. Its ortho-hydroxyl and aldehyde functionalities support direct condensation reactions, including Mannich-type cyclizations and Schiff base formation, with predictable regiochemistry. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, facilitating its use in multi-step synthesis workflows.
Synthesis
-
Route1
-
In-stock
139-85-5 -
74-88-4 - ~83%
-
In-stock
621-59-0
References
-
Japan Tobacco Inc. Patent: US6509352 B1, 2003 ;
-
-
Route2
-
In-stock
6346-05-0 - ~99%
-
In-stock
621-59-0
References
-
Jempty, Thomas C.; Gogins, Kitty A. Z.; Mazur, Yehuda; Miller, Larry L. Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4545 - 4551
-
-
Route3
-
18075-40-6 - ~93%
-
In-stock
621-59-0
References
-
Nawghare; Sakate; Lokhande Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 2 p. 291 - 302
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P271-P261-P280-P305+P351+P338-P312-P337+P313-P403+P233-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.53
- LogP 1.2133
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Isovanillin sigmaIsovanillin manufacturerIsovanillin priceIsovanillin structureIsovanillin SDSbuy IsovanillinIsovanillin supplierIsovanillin usesIsovanillin molecular weightprice of IsovanillinIsovanillin chemical name formula of Isovanillin