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CS-W001157 4
Total: USD 88.00

4-(Tetrahydro-2H-pyran-4-yl)aniline

  • CAS No. 62071-40-3

  • Cat. No. CS-W019196
  • Purity≥97%
  • MDL No.MFCD11506022
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

4-(Tetrahydro-2H-pyran-4-yl)aniline|CS-W019196

Structure of 62071-40-3

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Description

4-(Tetrahydro-2H-pyran-4-yl)aniline features a tetrahydropyran-4-yl group that enhances solubility and stability while the aniline moiety provides a reactive amine handle. This combination enables efficient incorporation into complex molecular architectures under mild conditions, offering improved handling compared to conventional anilines.

Application

4-(Tetrahydro-2H-pyran-4-yl)aniline serves as a versatile building block in medicinal chemistry, enabling the introduction of a stable, polar ether-containing aryl amine motif. The tetrahydropyran group enhances solubility and metabolic stability while maintaining compatibility with standard coupling reactions. Its bench-stable nature and tolerance to diverse reaction conditions facilitate efficient incorporation into complex scaffolds, particularly in the synthesis of bioactive heterocycles and API intermediates.

General Information

  • CAS No. 62071-40-3
  • Cat. No. CS-W019196
  • Purity ≥97%
  • MDL No. MFCD11506022
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅NO
  • Molecular Weight 177.24
  • Synonym(s) 4-(Oxan-4-yl)aniline
  • SMILES NC1=CC=C(C2CCOCC2)C=C1

Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.1628
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group :
Hazard Statements : H314-H318
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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