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CS-W001157 4
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2-Chlororesorcinol

  • CAS No. 6201-65-6

  • Cat. No. CS-W004897
  • Purity≥95%
  • MDL No.MFCD06658175

*For research and further manufacturing use only, not for direct human use.

2-Chlororesorcinol|CS-W004897

Structure of 6201-65-6

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General Information

  • CAS No. 6201-65-6
  • Cat. No. CS-W004897
  • Purity ≥95%
  • MDL No. MFCD06658175
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅ClO₂
  • Molecular Weight 144.56
  • Synonym(s) 2-Chloro Resorcinol
  • SMILES C1=CC=C(O)C(=C1O)Cl

Description

2-Chlororesorcinol features a chlorinated aromatic ring system with three hydroxyl groups, offering enhanced reactivity in electrophilic substitution and serving as a key intermediate in dye synthesis. The ortho-chloro substituent imparts electron-withdrawing character, stabilizing reaction intermediates under standard conditions. This bench-stable compound integrates readily into complex molecular architectures requiring precise functional group placement.

Application

2-Chlororesorcinol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted phenolic scaffolds. Its ortho-chloro and dihydroxy functionalities facilitate electrophilic substitution, Suzuki-Miyaura coupling, and directed metalation reactions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis of bioactive heterocycles and functionalized aromatics in medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • Environmental Science and Technology, , vol. 30, # 7 p. 2235 - 2242
  • Route2
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      17530-74-4
    • ~%
    • In-stock
      2-Chlororesorcinol|CS-W004897
      6201-65-6

    References

    • Chemosphere, , vol. 29, # 7 p. 1555 - 1560
  • Route3
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      36942-09-3
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      108-46-3
    • ~%
    • In-stock
      4-Chlorobenzene-1,3-diol|CS-W016374
      95-88-5
    • In-stock
      2-Chlororesorcinol|CS-W004897
      6201-65-6

    References

    • Zhurnal Obshchei Khimii, , vol. 3, p. 172,173, 174 Chem. Zentralbl., , vol. 105, # I p. 1476

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.7512
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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