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Structure of 101328-98-7
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2,4-Dichlorobenzene-1,3,5-triol features three hydroxyl groups positioned at the 1, 3, and 5 ring sites of a dichlorinated benzene scaffold. This arrangement imparts strong hydrogen-bonding capacity and enhanced solubility in polar media. The electron-withdrawing chlorine substituents modulate reactivity, favoring nucleophilic substitution at specific positions. The compound serves as a robust building block for functionalized aromatic systems in medicinal chemistry and materials science.
2,4-Dichlorobenzene-1,3,5-triol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted triazines and oxadiazoles via nucleophilic aromatic substitution. Its three phenolic hydroxyl groups exhibit high reactivity in coupling and cyclization reactions, while the dichloro substituents provide orthogonal handles for sequential functionalization. The compound demonstrates excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: