Lot numbers can be found on the outside label of a product:
Imidazo[1,2-a]pyridine-3-carbaldehyde
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CAS No. 6188-43-8
- Cat. No. CS-W007932
- Purity≥97%
- MDL No.MFCD07778354
*For research and further manufacturing use only, not for direct human use.
![Imidazo[1,2-a]pyridine-3-carbaldehyde|CS-W007932](https://file.chemscene.com/productPIC/CS-W007932.gif)
Structure of 6188-43-8
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General Information
- CAS No. 6188-43-8
- Cat. No. CS-W007932
- Purity ≥97%
- MDL No. MFCD07778354
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₆N₂O
- Molecular Weight 146.15
- Synonym(s) IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
- SMILES O=CC1=CN=C2C=CC=CN12
Description
Imidazo[1,2-a]pyridine-3-carbaldehyde features a rigid heteroaromatic core with a reactive aldehyde group at the 3-position. This scaffold integrates seamlessly into bioactive molecule design, offering enhanced metabolic stability and favorable binding interactions in target-directed synthesis. The aldehyde moiety enables efficient coupling reactions for diversification in medicinal chemistry campaigns.
Application
Imidazo[1,2-a]pyridine-3-carbaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its aldehyde functionality enables efficient derivatization via reductive amination, Grignard additions, and Wittig reactions. The scaffold exhibits robust bench stability and compatibility with common protecting group strategies, facilitating modular synthesis of complex molecular architectures.
Synthesis
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Route1
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In-stock
![Imidazo[1,2-a]pyridine|CS-W016589](https://file.chemscene.com/productPIC/CS-W016589.gif)
274-76-0 -
68-12-2 - ~33%
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In-stock
6188-43-8
References
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Del Corona; Pellegatta; Signorelli; Buran; Massaroli; Turba; Faini; Pagella Farmaco, Edizione Scientifica, 1981 , vol. 36, # 12 p. 994 - 1003
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Route2
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117459-95-7 - ~86%
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In-stock
6188-43-8
References
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Chandra Mohan, Darapaneni; Nageswara Rao, Sadu; Adimurthy, Subbarayappa Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1266 - 1272
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Route3
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In-stock
![1-(Imidazo[1,2-a]pyridin-3-yl)-N,N-dimethylmethanamine|CS-0517063](https://file.chemscene.com/productPIC/CS-0517063.gif)
2717-95-5 - ~%
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In-stock
6188-43-8
References
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US5760021 A1, ;
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 34.37
- LogP 1.1468
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 1
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Key Words
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