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6-Ethoxy-2-naphthoic acid

  • CAS No. 614754-39-1

  • Cat. No. CS-0160517
  • Molecule weight216.23
  • Purity≥97%
  • MDL No.MFCD18815314

*For research and further manufacturing use only, not for direct human use.

6-Ethoxy-2-naphthoic acid|CS-0160517

Structure of 614754-39-1

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General Information

  • CAS No. 614754-39-1
  • Cat. No. CS-0160517
  • Purity ≥97%
  • MDL No. MFCD18815314
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂O₃
  • Molecular Weight 216.23
  • Synonym(s) 6-(2-Hydroxyethyl)-1-naphthoic acid
  • SMILES O=C(O)C1=CC=C2C=C(OCC)C=CC2=C1

Description

6-Ethoxy-2-naphthoic acid features a naphthoic acid core with an ethoxy group at the 6-position, enhancing solubility and modulating electronic properties. This configuration supports direct functionalization in synthetic routes to bioactive molecules and advanced materials. The compound exhibits stability under standard conditions, facilitating handling in multi-step syntheses.

Application

6-Ethoxy-2-naphthoic acid serves as a versatile building block for naphthoic acid derivatives, enabling straightforward functionalization at the carboxylic acid and ethoxy positions. Its stability under standard reaction conditions facilitates coupling reactions, esterifications, and further derivatization in medicinal chemistry and materials synthesis. The molecule exhibits good solubility in organic solvents and is amenable to purification via recrystallization, supporting reliable use in scale-up and high-throughput workflows.

Synthesis

  • Route1
    • 2-Acetyl-6-methoxynaphthalene|CS-0229632
      3900-45-6
    • ~%
    • In-stock
      6-Ethoxy-2-naphthoic acid|CS-0160517
      614754-39-1

    References

    • Gray; Jones Journal of the Chemical Society, 1954 , p. 678,682
  • Route2

    References

    • Gray; Jones Journal of the Chemical Society, 1954 , p. 678,682
  • Route3
    • null|null
      124-38-9
    • ~%
    • In-stock
      6-Ethoxy-2-naphthoic acid|CS-0160517
      614754-39-1

    References

    • Hudson Journal of the Chemical Society, 1946 , p. 76

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.9367
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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